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Income, Investing  | December 28, 2018

The shares of ProQR Therapeutics N.V. have increased by more than 386.82% this year alone. The shares recently went up by 2.95% or $0.45 and now trades at $15.70. The shares of Equitrans Midstream Corporation (NYSE:ETRN), has jumped by 0.31% year to date as of 12/26/2018. The shares currently trade at $19.56 and have been able to report a change of -2.73% over the past one week.

The stock of ProQR Therapeutics N.V. and Equitrans Midstream Corporation were two of the most active stocks on Wednesday. Investors seem to be very interested in what happens to the stocks of these two companies but do investors favor one over the other? We will analyze the growth, profitability, risk, valuation, and insider trends of both companies and see which one investors prefer.

Profitability and Returns

Growth alone cannot be used to see if the company will be valuable. Shareholders will be the losers if a company invest in ventures that aren’t profitable enough to support upbeat growth. In order for us to accurately measure profitability and return, we will be using the EBITDA margin and Return on Investment (ROI), which balances the difference in capital structure. The ROI of PRQR is -87.00% while that of ETRN is 17.70%. These figures suggest that ETRN ventures generate a higher ROI than that of PRQR.

Liquidity and Financial Risk

The ability of a company to meet up with its short-term obligations and be able to clear its longer-term debts is measured using Liquidity and leverage ratios. The current ratio for PRQR is 11.40 and that of ETRN is 0.40. This implies that it is easier for PRQR to cover its immediate obligations over the next 12 months than ETRN. The debt ratio of PRQR is 0.08 compared to 13.47 for ETRN. ETRN can be able to settle its long-term debts and thus is a lower financial risk than PRQR.


PRQR currently trades at a P/B of 4.50, and a P/S of 105.41 while ETRN trades at a forward P/E of 11.51, a P/B of 19.27, and a P/S of 3.53. This means that looking at the earnings, book values and sales basis, PRQR is the cheaper one. It is very obvious that earnings are the most important factors to investors, thus analysts are most likely to place their bet on the P/E.

Analyst Price Targets and Opinions

The mistake some people make is that they think a cheap stock has more value to it. In order to know the value of a stock, there is need to compare its current price to its likely trading price in the future. The price of PRQR is currently at a -47.24% to its one-year price target of 29.76. Looking at its rival pricing, ETRN is at a -23.29% relative to its price target of 25.50.

When looking at the investment recommendation on say a scale of 1 to 5 (1 being a strong buy, 3 a hold, and 5 a sell), PRQR is given a 1.80 while 1.80 placed for ETRN. This means that analysts are equally bullish on their outlook for the two stocks stocks.

Insider Activity and Investor Sentiment

Short interest or otherwise called the percentage of a stock’s tradable shares currently being shorted is another data that investors use to get a handle on sentiment. The short ratio for PRQR is 2.81 while that of ETRN is just 2.61. This means that analysts are more bullish on the forecast for ETRN stock.


The stock of ProQR Therapeutics N.V. defeats that of Equitrans Midstream Corporation when the two are compared, with PRQR taking 5 out of the total factors that were been considered. PRQR happens to be more profitable, generates a higher ROI, has higher cash flow per share, higher liquidity and has a lower financial risk. When looking at the stock valuation, PRQR is the cheaper one on an earnings, book value and sales basis. Finally, the sentiment signal for PRQR is better on when it is viewed on short interest.

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