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Since the Coronavirus came into our lives this slice of the stock market has given ordinary people the chance to multiply their money by 96% in 21 days on JP Morgan.

Investing, Stocks  | October 13, 2021

As Q4 gets into full swing, we can take a moment to look back over our shoulders at where we’ve come from. The sustained upward trend of the markets is obvious from this view, and the recent downturn in the market appears as a bump against some otherwise solid gains. Even so, there are reasons for concern right now.

The COVID pandemic hasn’t gone away – and it doesn’t look like it will go away either. The September jobs numbers were weak, and unemployment only fell because too many people left the workforce. Which brings us to the main cause for concern, the Biden Administration wants to pump up social spending, even though we’ve seen evidence that increased government money has kept people out of the workforce and exacerbated a labor shortage.

But the US economy is nothing if not resilient – it has proven that over the last couple of centuries. Its underlying strengths, including an industrious people with access to continent-wide resources, are enough to bulldoze all sorts of troubles.

Writing from Raymond James, CIO Larry Adams sees four points that are likely to provide an economic cushion as 2021 winds down: “Gradually filling the record 10+ million job openings; Increasing wages; Rebuilding depleted inventories; Boosting business capital expenditures.”

At the bottom line, says Adams, “The economy should keep climbing at an above-trend economic pace through at least 2022.” Long-term, in his view, it’s a bullish environment for stock investors.

"Temporary periods of fatigue are normal and given the supportive long-term fundamentals, equities should offer some attractive buying opportunities. U.S. equities remain our preferred territory, as the strong economic recovery and magnitude of earnings growth make it the leader of the pack," Adams summed up.

Tarsus Pharmaceuticals (TARS)

We’ll start with Tarsus Pharma, a biomedical research company that describes itself as involved in late clinical stage research in novel therapeutics for conditions with currently limited options for treatment. The company has a varied pipeline, in which the two main thrusts are the treatment of Demodex blepharitis, a disease of inflammation of the eyelids, caused by a parasitic mite, and the treatment of Lyme disease, a dangerous viral disease spread by ticks. Both have substantial patient bases in the US, with unmet medical needs.

To meet those needs, Tarsus has two major clinical trial programs ongoing. TP-03 is a novel therapeutic drug under investigation for the treatment of Demodex blepharitis. As of the end of Q2 this year, the company had reported positive from the Saturn-1 pivotal trial, and had initiated the Saturn-2 pivotal trial, a second Phase 3 study of the safety and efficacy of TP-03. Topline data from Saturn-2 is expected in 1Q22.

On the Lyme disease front, Tarsus is investigating TP-05. This drug is currently under evaluation in the Callisto Phase 1 trial. The trial is designed to determine the safety, tolerability, and pharmacological action of TP-05. The drug is intended to act against the tick that spreads Lyme disease. In another application, Tarsus is initiating a study of TP-05 as an agent against the spread of malaria, by acting against the mosquitos that spread the malaria parasite.

Tarsus is conducting its clinical trials as part of a strategic partnership with the Chinese company LianBio, for which Tarsus received $22 million in license fees in Q2. In addition to the license fees, Tarsus had $177 million in liquid assets to continue its clinical trial program.

Covering TARS for Raymond James, analyst Dane Leone rates the stock a Strong Buy along with a $65 price target that suggests a robust 169% upside potential. Leone's thesis remains centered on TP-03 in Demodex blepharitis, and he sees disconnect between the company’s market capitalization and TP-03's market opportunity. (To watch Leone’s track record, click here)

“The primary investor controversy surrounding the market potential of TP-03 has been 1) expected utilization, and 2) medical insurance coverage. We agree that reimbursement and pricing via medical insurance will continue to be a debate until clearer feedback can be garnered from both pivotal studies, but based upon our survey results, we do think that there could be good adoption within the ophthalmology community. Overall, we now forecast peak sales of TP-03 of ~$453m during 2030E…”

Overall, Tarsus gets another Strong Buy from the analyst consensus view, based on a unanimous 4 recent analyst reviews. The shares are priced at $24.20 and their average target of $59.75 implies ~147% upside from that level.

ChemoCentryx (CCXI)

Next up is ChemoCentryx, another biopharma research firm. This company’s focus is on the treatment of autoimmune diseases and inflammatory disorders, as well as cancer. The company’s pipeline is directed mainly at orphan and rare diseases, an area that frequently has a high unmet medical need.

Shares in ChemoCentryx have had a roller-coaster years. The stock plunged from $48 to $10 from May 3 to May 7 this year, when the FDA’s advisory committee split 10 to 8 in its vote on approval of avacopan, the company's treatment for a rare kidney disease. The split decision was taken as an indication that the regulatory agency have serious questions about the drug’s efficacy in treatment, although the committee did lean toward approval.

That approval was given earlier this month, and the shares jumped from $19 to $40 between October 8 and October 11. Avacopan is the first new treatment for ANCA-associated vasculitis to be approved in over a decade. ChemoCentryx will market the drug in the US under the name Tavneos, and aims at a patient base of some 9,500 people. With an annual price of $200,000 per patient for Tavneos, analysts expect to see sales revenue reach $1.3 billion by 2035.

In his coverage of CCXI for Raymond James, analyst Steven Seedhouse sees the avacopan approval as a game changer for the stock.

“Regulatory risk is removed and our conviction that avacopan (now Tavneos) will be a blockbuster if approved is unchanged now that it is in fact approved with a very favorable label… Our peak sales estimate is ~$1.8B in the U.S., with assumed peak royalties of ~$130M from the EU (pending approval) and Japan (approved) combined," Seedhouse cheered.

Seedhouse follows his bullish comments with a one-year price target of $107, indicating his confidence in an upside of 164% for the next 12 months, and a Strong Buy rating on the stock

ChemoCentryx currently has a Strong Buy rating from the analyst consensus, based on 8 analyst reviews, breaking down to 7 Buys and 1 Hold. The shares are priced at $40.5 and have an average price target of $65.33, suggesting a one-year potential upside of ~61%.

I3 Verticals (IIIV)

For the last stock, we’ll change gears and shift over to the online payment sector. This is a crowded segment of the digital finance world, and one that has potential for serious gains in the post-COVID world. I3 bills itself as delivering solutions – solutions in payments and software for small and medium businesses and non-profits. The company boasts customers in education, healthcare, retail, government, and property management, among others, and offers products in point-of-sale, e-commerce, and mobile payment transactions.

During the past several months, I3 has been actively pursuing an acquisition strategy to expand the company’s footprint. Back in April, the company reported two such moves, in the healthcare and public sector verticals. The transactions cost a combined $40 million. More recently, on October 4, I3 reported another healthcare vertical acquisition, this one worth $60 million.

The acquisition moves coming this year have coincided with rising revenues. The company has reported four consecutive quarter-over-quarter revenue gains since business bottomed out in Q3 of fiscal 2020. The most recent quarterly revenue, for fiscal 3Q21, came in at $61.9 million, up 96% year-over-year. For the first half of 2021, I3 reported processing over $17 billion in total payment volume.

Raymond James analyst John Davis takes an optimistic view of I3's prospects following the recent healthcare vertical acquisition, writing: "Management continues to execute on its M&A strategy as the company closed yet another deal that not only makes strategic sense but is also financially attractive... Strategically, we believe the acquisition represents the long awaited healthcare platform deal with significant cross-sell opportunity... Although the stock has certainly underperformed YTD... we believe it has created a tremendous buying opportunity..."

To this end, Davis gives IIIV shares a Strong Buy rating, with a $40 price target that implies an upside of 68% in the coming year.

I3 Verticals also has a Strong Buy from the analyst consensus, based on 5 positive reviews against a single Hold. The stock’s $39.17 average price target suggests it has room to grow 65% from the $23.72 share price in the next year.

A revolutionary initiative is helping average Americans find quick and lasting stock market success.

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